This presentation provides an introduction to the concept of grading medical evidence, including a review of the basic concepts of evidence-based medicine (EBM), a short history of EBM, an overview of evidence-rating schemes, and thoughts on the integration of EBM into clinical practice. This material is a revised version of a CME presentation at Sacred Heart Hospital, Eau Claire, Wisconsin, 10 February 2009 FMDRL_ID: 2136#ResourcetoShare