This resource is a compilation of materials from a student-led improvement science curriculum adapted to be delivered virtually during COVID-19 to first-year medical students in a longitudinal preclinical program. The attachments include 1) screenshots of run chart and pareto chart student exercises in the COVID-19 context; 2) a three-question project brainstorming exercise for students to explore project topics; 3) a project management excel template for students to document their Plan-Do-Study-Act cycles;4) a post-session online survey form; and 4) PowerPoint presentations for each didactic session. This resource is submitted as an accompaniment to a PRiMER rapid original research article on COVID-19 educational issues describing the implementation and outcomes of this activity. #improvementscience #COVID-19