The STFM Spring Conference 2022 at Indianapolis, IN. Drs. Yury Parra and Yasmin Hashemi discuss the hand-in-hand imperatives for caring for people who have HIV. From health policy to social determinants of health, particularly housing instability, management of HIV most certainly should include addressing and advocating for these concerns. Lastly, embracing the model of HIV as a chronic disease will ensure a new era of primary care for persons with HIV.Acknowledgements to Drs. Marshal Miller and Radeeb Akhtar.